Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia
نویسندگان
چکیده
منابع مشابه
Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia
BACKGROUND Aspirin eugenol ester (AEE) is a promising drug candidate for treatment of inflammation, pain and fever and prevention of cardiovascular diseases with less side effects. The experiment will be conducted to investigate the efficacy of AEE on curing hyperlipidemia in Wistar rats. The rats were fed with high fat diet (HFD) for 8 weeks to induce hyperlipidemia. RESULTS Compared with th...
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15 صفحه اولPreventive Effect of Aspirin Eugenol Ester on Thrombosis in κ-Carrageenan-Induced Rat Tail Thrombosis Model
Based on the prodrug principle, aspirin eugenol ester (AEE) was synthesized, which can reduce the side effects of aspirin and eugenol. As a good candidate for new antithrombotic and anti-inflammatory medicine, it is essential to evaluate its preventive effect on thrombosis. Preventive effect of AEE was investigated in κ-carrageenan-induced rat tail thrombosis model. AEE suspension liquids were ...
متن کاملImpact of Aspirin Eugenol Ester on Cyclooxygenase-1，Cyclooxygenase-2，C-reactive protein，Prothrombin and Arachidonate 5-lipoxygenase in Healthy Rats
Aspirin eugenol ester (AEE) is a promising drug candidate, which is used for the treatment of inflammation, pain and fever and the prevention of cardiovascular diseases. This study focuses on the effect of AEE on five proteins which are related to inflammation and thrombosis, including cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), C-reactive protein (CRP), prothrombin (FII) and arachidona...
متن کاملImpact of Aspirin Eugenol Ester on Cyclooxygenase-1，Cyclooxygenase-2，C-reactive protein，Prothrombin and Arachidonate 5-lipoxygenase in Healthy Rats
Aspirin eugenol ester (AEE) is a promising drug candidate, which is used for the treatment of inflammation, pain and fever and the prevention of cardiovascular diseases. This study focuses on the effect of AEE on five proteins which are related to inflammation and thrombosis, including cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), C-reactive protein (CRP), prothrombin (FII) and arachidona...
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ژورنال
عنوان ژورنال: BMC Veterinary Research
سال: 2015
ISSN: 1746-6148
DOI: 10.1186/s12917-015-0523-5